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Epidermal Cyst in an Intrapancreatic Accessory Spleen

Open AccessPublished:September 23, 2022DOI:https://doi.org/10.1016/j.gastha.2022.09.007
      A 59-year-old asymptomatic woman with no disease history presented to our institution for investigation of a pancreatic tail mass. Hematological parameters were within normal ranges, including serum carcinoembryonic antigen levels and carboxyhydrate antigen 19-9. Computed tomography revealed a strongly enhanced solid peripheral mass with an intracystic component in the pancreatic tail (Figure A, arrow). Magnetic resonance imaging revealed a cystic lesion on the T2 image surrounded by a solid component with density and intensity levels similar to those in the spleen parenchyma (Figure B, arrow). Endoscopic ultrasonography showed a solid hyperechoic 20-mm mass and an intracystic hypoechoic component showing stronger enhancement by Sonazoid (MSD Inc) than the pancreatic parenchyma (Figure C, arrow). Laparoscopic distal pancreatectomy was used for diagnosis. Pathological examination revealed a white and red sinus of the ectopic spleen in the pancreatic tail, with a unilocular cyst lined with stratified squamous epithelium, indicating an epidermal cyst in the intrapancreatic accessory spleen (Figure D, arrows).