Background and aims
Abbreviations:ALT (alanine aminotransferase), aORs (adjusted odd ratios), ASE (American Society of Echocardiography), AST (aspartate aminotransferase), BNP (B-type natriuretic peptide), CI (confidence interval), CVP (central venous pressure), eGFR (estimated glomerular filtration rate), GLS (global longitudinal strain), HDL (high-density lipoprotein), HFpEF (heart failure with preserved ejection fraction), HFrEF (heart failure with reduced ejection fraction), IVST (interventricular septal thickness), LA (left atrium), LDL (low-density lipoprotein), LV (left ventricular), LVDd (left ventricular end-diastolic), LVDs (left ventricular end-systolic diameter), LVEF (left ventricular ejection fraction), LVMI (left ventricular mass index), MACE (major adverse cardiovascular events), NAFLD (nonalcoholic fatty liver disease), PWT (posterior wall thickness), RWT (relative wall thickness), TR (tricuspid regurgitation)
Publication stageIn Press Accepted Manuscript
Grant support: This work was supported by grants from the Osaka Medical Research Foundation for Intractable Disease [28-2-6] to Chisato Okamoto, the Japan Arteriosclerosis Prevention Fund, and the Japan Society for the Promotion of Science KAKENHI [JP18K15910] to Takuya Hasegawa and in part by grants from the Japan Heart Foundation to Masafumi Kitakaze.
Disclosures: None to declare.
Writing assistance: Editage [http://www.editage.com] for editing and reviewing this manuscript for the English language.
Chisato Okamoto, Osamu Tsukamoto, and Masafumi Kitakaze were the principal investigators in this study. Chisato Okamoto wrote the manuscript and performed statistical analyses of the data. Osamu Tsukamoto and Masafumi Kitakaze critically revised this manuscript. Shin Ito was responsible for the data analysis of the Arita-cho cohort study. All authors contributed to the interpretation of the results. All the authors critically read and edited several drafts prior to submission. All authors have read and approved the submitted version.
Data transparency statement: Data, analytical methods, and study materials will not be made available to other researchers.
Ethical Statement: The corresponding author, on behalf of all authors, jointly and severally, certifies that their institution has approved the protocol for any investigation involving humans or animals and that all experimentation was conducted in conformity with ethical and humane principles of research.
User LicenseCreative Commons Attribution (CC BY 4.0) |
- Read, print & download
- Redistribute or republish the final article
- Text & data mine
- Translate the article
- Reuse portions or extracts from the article in other works
- Sell or re-use for commercial purposes
Elsevier's open access license policy